Left ventricular regional relaxation and its nonuniformity in hypertrophic nonobstructive cardiomyopathy.

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Left ventricular regional relaxation and its nonuniformity in hypertrophic nonobstructive cardiomyopathy.

BACKGROUND Regional nonuniformity has been suggested to be closely related to left ventricular (LV) relaxation in diseased heart. The purpose of the present study was to assess LV global and regional relaxation in patients with nonobstructive hypertrophic cardiomyopathy (HCM). METHODS AND RESULTS Left ventriculography was conducted simultaneously with pressure micromanometry in 10 normal cont...

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BACKGROUND Nonuniformity is a determinant of diastolic function. In patients with hypertrophic cardiomyopathy, hypertrophy, abnormal calcium handling, and regional ischemia can also play a role. This study was designed to assess regional mechanics, asynchrony, and asynergy in patients with hypertrophic cardiomyopathy. METHODS AND RESULTS Nine control subjects and 22 patients with hypertrophic...

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ژورنال

عنوان ژورنال: Circulation

سال: 1991

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.84.4.1496